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What is OMRF?
Our History
Our Values
OMRF Leadership
Board of Directors
Disease Research
The Economic Impact
of OMRF
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Founded in 1946, OMRF is one of the nation’s oldest and most respected
nonprofit biomedical research institutes. Located in Oklahoma City, OMRF fosters a worldwide
reputation for excellence by following an innovative cross-disciplinary approach to medical
research.
OMRF scientists are dedicated to understanding and developing more effective
treatments for human disease, focusing on such critical research areas as heart disease,
cancer, lupus and Alzheimer’s disease. OMRF is home to Oklahoma’s only Howard Hughes Medical
Institute investigator, and with more than 600 U.S. and international patents, OMRF ranks
among the nation’s leaders in patents per scientist.
Breakthroughs in our labs have led to three FDA-approved drugs, including
the first for a deadly blood infection that claims 200,000 American lives each year. OMRF also
discovered the enzyme believed responsible for Alzheimer’s disease, and a drug born at OMRF
was the first licensed under the European Union’s centralized procedure.
Along the way, OMRF has garnered worldwide media attention, from leading
scientific publications like The New England Journal of Medicine and Science to The New York
Times and The Wall Street Journal. By pushing the boundaries of biomedical science, our
researchers are helping to win the war against human disease, one discovery at a time.

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